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NFL Week Three Picks

Week Two Review and Upcoming Predictions

Our NFL Week Three picks provides sports bettors quick bets based on current team situations and matchups. In creating NFL Week Three picks we’ve recapped Week Two to put each team in perspective and then focused on what we find are the top five best bets for Sunday, September 22, 2019. Of course, every week of the NFL is filled with surprises. Thus, what should be a blowout could end up in an upset and what appears to be a close contest could result in a run away victory for one football team.

Along with these down and dirty NFL Week Three picks, today and every Sunday, Betting Brain offers free picks that involve extended and deep analysis. Also, check this website periodically throughout the week for fantastic sports betting opportunities.  In doing so, make sure to use our in-depth analysis all 32 NFL teams for the 2019 season. Each of our analytical articles offers essential and important statistics, facts, and insights.

NFL Week Three Picks – AFC Roundup

AFC East

  • Buffalo Bills
    • The Bills (2-0) returned to Giants Stadium where they beat the Jets in Week One and this time beat the NYG 28-14. QB Josh Allen went 19-30 and tossed a TD pass as well as rushing for one of three Buffalo ground scores.
  • New England Patriots
    • The Patriots (2-0) easily beat Miami 43-0 in the one game Antonio Brown would play as a Pat.  Tom Brady tossed two TD passes while the New England D posted seven sacks, eight TFL, and took in four picks, running back two for scores.
  • New York Jets
    • The Jets (0-2) lost to the Browns 3-23 in Monday Night Football. NY quarterback Sam Darnold did not play due to mononucleosis. Trevor Siemian started but suffered an ankle injury in quarter two and Luke Falk, who was on the practice squad the week prior, came in.
  • Miami Dolphins
    • The Dolphins (0-2) were once again humiliated in Week Two, as they had been in Week One by the Ravens. This time it was the Patriots destroying them 43-0. Both Josh Rosen and Ryan Fitzpatrick saw action with Rosen tossing one INT and Fitzpatrick three.

AFC North

  • Baltimore Ravens
    • The Ravens (2-0) beat the Cardinals 23-17 for their second win of the season. Baltimore QB Lamar Jackson passed for 272 yards and rushed for another 120. He threw two TD passes and no INTs. Jackson completed 24-27 pass attempts.
  • Cincinnati Bengals
    • The Bengals (0-2) were dominated by the 49ers, as Andy Dalton and company lost to SF 17-41. Daltom completed just 26 of 42 passes for 311 yards. He threw two TD strikes and one INT while being sacked four times for 20 yards.  The Bengals rushed for just 25 yards.
  • Cleveland Browns
    • Against the Jets, Cleveland (1-1) QB Baker Mayfield Browns was 19-35 for one TD and one pick. Odell Beckman caught an 89-yard TD pass and RB Nick Chubb rushed for another score as the Browns handed the Jets their second loss 23-3
  • Pittsburgh Steelers
    • The Steelers (0-2) lost to the Seahawks 26-28, QB Ben Roethlisberger did not play the second half due to an elbow issue. Backup Mason Rudolph went 12-19 for 112 yards and hot for two scores. He tossed one pick. The Pittsburgh defense posted four sacks and 7.5 TFL.

AFC South

  • Houston Texans
    • The Texans (1-1) were in a second close game this season. They lost their first game to the Saints 28-30. This time, Houston stopped a two-point conversion attempt by Jacksonville with 36 seconds left to win the game 13-12. Houston QB Deshaun Watson was unremarkable as he passed for 159 yards, tossing no TD passes and no INTs. Watson did score on a short TD rush.
  • Indianapolis Colts
    • The Colts (1-1) came back to be beat the Titans 19-17. QB Jacoby Brissett completed 17 of 28 attempts for 146 yards.  He hit for three TDs and gave up one pick. T.Y. Hilton had four catches for 43 yards and one score. RB Jordan Wilkins rushed for 82 yards on five carries. The Colts D posted four sacks and 6.5 TFL.
  • Jacksonville Jaguars
    • The Jags (0-2) lost their second game of the season, as the Texans beat them 13-12. QB Gardner Minshew completed 23 of 33 passes for 213 yards and one TD and no INTs. D.J. Chark had seven catches for 55 yards and one TD. Minshew fumbled three times, losing one.
  • Tennessee Titans
    • In week two, the Titans (1-1) lost their home opener 17-19 to Indy. QB Marcus Mariota was 19 of 28 for 154 yards and one score. He did not throw an interception. RB Derrick Henry rushed for 82 yards on 15 carries and one score. He also caught one pass for 75 yards and one score. The Titan D had one pick, three sacks, and three TFL.

AFC West

  • Denver Broncos
    • The Broncos (0-2) lost to the Bears 14-16. QB Joe Flacco completed 35 of 50 pass attempts for 252 yards and one score. He tossed one INTs and was sacked twice. WR Emmanuel Sanders has 11 catches for 98 yards and one score. Denver kicker Brandon McManus kept the team in the game, as he hit two of two FGs.
  • Kansas City Chiefs
    • The Chiefs (2-0) beat the Raiders 28-10 as Patrick Mahomes threw four TD passes and no INTs. He was 30-44 for 443 yards. WR DeMarcus Robinson had six catches for 172 yards a two scores while TE Travis Kelce has seven receptions for 107 yards and one TD. RB LeSean McCoy carried the ball 11 times for just 23 yards. The KC defense recorded 7.5 TFL and three sacks.
  • Los Angeles Chargers
    • The Chargers (1-1) were ahead of the Lions at halftime 10-6, but they lost 13-10. QB Phillip Rivers was 21 of 36 for 293 yards. He tossed one INT and did not throw a TD pass. RB Austin Ekeler rushed for 66 yards and one score on 17 carries. Ekeler, who fumbled once and lost the ball, also caught six passes for 67 yards.
  • Oakland Raiders
    • Oakland (1-1) lost to the Chiefs 10-28. The Raiders led at halftime 14-0. QB Derek Carr completed 23 of 38 attempts for one score and two INTs. Carr was sacked three times for 20 yards and fumbled twice. RB Josh Jacobs rushed for 99 yards on 12 carries. He did not score. The Oakland D did not have an INT and recorded just two sacks. They did have 10 TFL.

NFL Week Three Picks – NFC Roundup

NFL Week Two – NFC East

  • Dallas Cowboys
    • The Cowboys (2-0) beat the Redskins 31-21 as Dak Prescott threw three TD passes and went 26-30 for 269 yards. He posted one pick. Three different receivers caught touchdown passes. Ezekiel Elliot rushed for 111 yards on 23 carries for one TD.
  • New York Giants
    • The Giants (0-2) were beat for a second straight week as QB Eli Manning was 26-45 for 250 yards and one TD. He also three two picks. RB Saquon Barkley had 18 rushes  for 107 yards and one score.
  • Philadelphia Eagles
    • The Eagles (1-1) lost to the Falcons 20-24.took down the Skins 32-27. WR DeSean Jackson averaged 19.3 YPC. He caught eight passes for 154 yards and two scores. QB Carson Wentz completed 23 of 43 of his passes for one score and 231 yards. Wentz tossed two picks, DeSean Jackson (groin) and Alshon Jeffery (calf), were taken out of the game. Jeffery led the team with eight catches for 107 yards and one TD.
  • Washington Redskins
    • The Redskins (0-2) lost 31-21 to the Cowboys as Washington QB Case Keenum completed 26 of 37 passes for 221 yards and two TDs. WR Terry McLaurin made five catches for 62 yards and one score. The team recored just 47 rushing yards. Safety Monte Nicholson grabbed one pick

NFC North

  • Chicago Bears
    • The Bears (1-1) won their first game of the season as PK Eddy Pineiro, who was three of three on FGs, hit a 53-yard attempt as time ran out for the win. QB Mitchell Trubisky was 16-27 for 120 yards. Chicago rushed for 153 yards as RB David Montgomery carried the ball 18 times for 62 yards and one score. The defense posted one pick, two sacks, and four TFL.
  • Detroit Lions
    • After tying with the Cardinals 27-27 in Week One, the Lions (1-0-1) remained undefeated in Week Two as they beat the Chargers 13-10. QB Matthew Stafford completed 22 of of 30 passes for 245 yards and two TDs and two picks. WR Kenny Golladay had eight catches for 117 yards and one score. PK Matt Prater missed one of two XPs and also missed his only FG try of the game.
  • Green Bay Packers
    • The Packers (2-0) led the Vikings from the start and never looked back as QB Aaron Rodgers threw for 209 yards and two scores as he completed 22 of 34 passes. WR DeVante Adams has seven catches for 106 yards, while RB Aaron Jones has 23 carries for 116 yards and one score. edged out the Bears 10-3 as Aaron Rodgers connected on 18-30 for one TD and no INTs. Rodgers was sacked twice times and lost one fumble. The Green Bay defense hauled in two INTs. The Pack took the game 21-16.
  • Minnesota Vikings
    • The Vikings (1-1) lost to Green Bay 16-21 as Minnesota QB Kirk Cousins went 14-32 for 230 yards and one TD and two picks. WR Stefon Diggs caught one TD pass. RB Dalvin Cook had 20 carries for 154 yards and a score. In the loss, Minnesota posted 198 rushing yards.

NFC South

  • Atlanta Falcons
    • Falcon (1-1) QB Matt Ryan did not have a great game, as he tossed three picks and completed of 27 of 43 passes (63%). Ryan did throw three TD passes as Atlanta beat the Eagles 24-20. Although WR Julio Jones had just five catches, two were for TDs. He accumulated 106 yards. Wideout Calvin Ridley made eight catches for 105 yards and one score.
  • Carolina Panthers
    • The Panthers (0-2) lost their second straight game of the season, losing 14-20 to the Bucs. Cam Newton had another bad game, as he once again completed less than 50% of his passes for 333 yards and no scores. Newton also fumbled once, as he lost the ball. The Carolina rush attack posted just 39 yards.
  • New Orleans Saints
    • The Saints (1-1) lost to the Rams 3-27 as star QB Drew Brees stood on the sidelines after injuring his hand. Backup Terry Bridgewater completed 17 of 30 passes for 165 yards. He did not throw a TD pass nor did he toss an INT. The Saints rushed for just 57 yards with RB Alvin Kamara gaining 45 yards on 13 carries. Michael Thomas made 10 receptions for 89 yards.
  • Tampa Bay Buccaneers
    • The Bucs (1-1) beat the Panthers 20-14 to notch their first victory of the season. QB Jameis Winston was 16 of 25 for 208 yards and one TD. Winston did not post an INT. WR Chris Godwin caught eight passes for 121 yards and one TD. RB Peyton Barber recorded 82 yards and one score on 23 carries.

NFC West

  • Arizona Cardinals
    • The Cardinals (0-1-1) lost to Baltimore 17-23, as QB Kyler Murray hit 25 of 40 pass attempts for 349 yards but tossed neither a TD pass nor a pick. He was sacked three times for 20 yards. In their first loss of the season, Arizona posted just 20 rushing yards.
  • Los Angeles Rams
    • The Rams (2-0) took down the Saints 27-9 for their second win of this young season. QB Jared Goff hit for one TD pass, as he completed 19 of 28 passes for 283 yards. Goff lost one fumble. WR Cooper Kupp recorded five catches for 120 yards and Brandin Cooks had three catches for 74 yards and one score. Todd Gurley rushed for 63 yards and one score.
  • San Francisco 49ers
    • S.F. (2-0) tops the NFC West as they beat Arizona 41-17.  QB Jimmy Garoppolo hit for three scores while completing 17 of 25 passes. He threw one pick. In the win, the Niners rushed for 259 yards with Matt Breida gaining 121 yards on 12 attempts. Breida is averaging 5.9 YPA thus far this season. Frisco had four sacks and eight TFL.
  • Seattle Seahawks
    • The Seahawks (2-0) are off to their best start in six years as they won yet a second straight close game beating the Steelers 28-26 in a comeback win. QB Russell Wilson was 29-34 for three TD passes and 300 yards. Seattle rushed for 151 yards and Rashad Penny, who had 62 of those yards on 10 carries, crossed the goal line once. The Hawks fumbles twice, losing both.

NFL Week Three Pick  – Quick Predictions

Our NFL Week Three picks offers five quick predictions. Along with this NFL Week Three picks article, remember that we also offer premium free pro football picks each and every week as well as free NCAAF previews and predictions. You can check NFL standings going into Week Three here.

  1. Cincinnati @ Buffalo at 1:00 pm – The Bills are on a roll and the Bengals are struggling. Take Buffalo at -6.0.
  2. New England @ NY Jets at 1:00 pm – The Pats are -21. We see no reason to not take explosive New England versus the hapless Jets. Bet the Patriots as three TD favorites.
  3. Miami @ Dallas at 1:00 pm – One of the best teams in the NFC meet one of the worst in the NFL. Bet the Cowboys at -21.5.
  4. Pittsburgh @ San Francisco at 4:25 pm – We like the Garropollo-led Niners at -6.5.
  5. New Orleans @ Seattle at 4:25 pm – Brees is out, but the Saints still have a good team. The Hawks are at home. The spread is -4.5 or 5.0 with the Seahawks being favored. We’re tasking New Orleans at +5.0.


Paul has been writing about sports betting and sports for more than a decade, offering picks on the NFL, MLB, NHL, and NBA, as well as on college sports and European football. He's written thousands of season and post-season previews, innumerable articles on sports betting strategies, and various books on sports and sports betting.

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